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  • AG 1478

    EGFR kinase inhibitor

    Catalog No. SIH-425

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    CAS No. 153436-53-4
    Molecular Formula C16H14ClN3O2
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    SIH-425_AG_1478_Chemical_Structure.png

  • AG 1517

    EGFR kinase inhibitor

    Catalog No. SIH-427

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    CAS No. 153436-54-5
    Molecular Formula C16H14BrN3O2
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    SIH-427_AG_1517_Chemical_Structure.png

  • AG 494

    EGFR kinase inhibitor

    Catalog No. SIH-491

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    CAS No. 133550-35-3
    Molecular Formula C16H12N2O3
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    SIH-491_AG-494_Chemical_Structure.png

  • AG 879

    NGFR kinase inhibitor

    Catalog No. SIH-429

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    CAS No. 148741-30-4
    Molecular Formula C18H24N2OS
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    SIH-429_AG-879_Chemical_Structure.png

  • AG-1296

    PDGFR kinase inhibitor

    Catalog No. SIH-426

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    CAS No. 146535-11-7
    Molecular Formula C16H14N2O2
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    SIH-426_AG-1296_Chemical_Structure.png

  • AG490

    JAK-2 kinase inhibitor

    Catalog No. SIH-428

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    CAS No. 133550-30-8
    Molecular Formula C17H14N2O3
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    SIH-428_AG-490_Chemical_Structure.png

  • AHA1 Protein

    Human Recombinant AHA1 Protein

    Catalog No. SPR-300

    5.00 out of 5 based on 1 customer rating
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    Expression System E. coli
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    SPR-300_AHA1_Protein_SDS-Page.png

  • AHA1 Protein

    Human Recombinant AHA1 Protein

    Catalog No. SPR-309

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    Expression System E. coli
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    SPR-309_AHA1-Protein-SDS-Page-1.png

  • AHA1 Protein (Discontinued)

    Mouse Recombinant AHA1 Protein

    Catalog No. SPR-311

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    Expression System E. coli
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    SPR-311_AHA1_Protein_SDS-Page.png

  • AHA1 Protein (Discontinued)

    Yeast Recombinant AHA1 Protein

    Catalog No. SPR-314

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    Expression System E. coli
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    SPR-314_AHA1_Protein_SDS-Page.png

  • AHA2 Protein (Discontinued)

    Human Recombinant AHA2 Protein

    Catalog No. SPR-312

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    Expression System E. coli
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  • AHA2 Protein (Discontinued)

    Mouse Recombinant AHA2 Protein

    Catalog No. SPR-313

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    Expression System E. coli
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    SPR-313_AHA2-Protein-SDS-Page-1.png

  • AICAR

    Autophagy inducer

    Catalog No. SIH-402

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    CAS No. 2627-69-2
    Molecular Formula C9H14N4O5
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    SIH-402_AICAR_Chemical_Structure.png

  • Alpha Synuclein Monomers

    Human Recombinant Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-321

    5.00 out of 5 based on 1 customer rating
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    Expression System E. coli
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    SPR-321_Alpha-Synuclein-Protein-Monomer-Thioflavin-T-assay-1.png
    SDS-Page of huma alpha synuclein monomer (SPR-321)

  • Alpha Synuclein Monomers

    Human Recombinant Alpha Synuclein Monomers (Type 2)

    Catalog No. SPR-316

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    Expression System E. coli
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    SPR-316_Alpha-Synuclein-Protein-Monomer-Protein-SDS-Page-1.png
    Alpha Synuclein monomers (SPR-316) do not form new alpha synuclein fibrils when combined with Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by a limited increase in fluorescence intensity by Thioflavin T over time.Alpha Synuclein Monomer RT-QuiC AssayΑlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.LDH assay shows effect of alpha synuclein monomers on mouse primary neuronsMTT assay shows effects of alpha synuclein monomers on mouse primary neurons

  • Alpha Synuclein Pre-formed Fibrils

    Human Recombinant Alpha Synuclein PFFs (Type 2)

    Catalog No. SPR-317

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    Expression System E. coli
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    SPR-317_Alpha-Synuclein-Preformed-Fibrils-Protein-TEM-4.png
    TEM of Type 2 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-317)Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.SDS-Page of Type 2 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-317)Type 2 alpha synuclein Pre-formed fibrils (SPR-317) do not seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) at the same rate as Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by lower fluorescence intensity values of Thioflavin T over time.Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).Toxicity results comparing Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2) and Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)LDH assay shows effect of alpha synuclein PFFs on mouse primary neuronsMTT assay effects of alpha synuclein PFFs on mouse primary neurons