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Research Area

Apoptosis

Apoptosis is a process of deliberate suicide by a cell in a multi-cellular organism. It is one of the main types of programmed cell death, and involves an orchestrated series of biochemical events leading to a characteristic cell morphology and death. The apoptotic process is executed in such a way as to safely dispose of cell corpses and fragments.

Apoptosis can occur when a cell is damaged beyond repair, infected with a virus, or undergoing stress conditions such as starvation. The tumor-suppressing gene p53 can also induce apoptosis via DNA damage or toxic chemicals.

The decision for apoptosis can come from the cell itself, from the surrounding tissue, or from a cell that is part of the immune system. Because of this connection with the immune system, apoptosis is studied in an extensive variety of diseases including HIV and cancer.


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Product Category Clone # Catalog # Size Description Research Area Price Place Order
Actinomycin D Small Molecules N/A SIH-245-10MG 10mg Transcription inhibitor Apoptosis $107.00 USD Add to Cart
Actinomycin D Small Molecules N/A SIH-245-50MG 50mg Transcription inhibitor Apoptosis $399.00 USD Add to Cart
Amifostine Small Molecules N/A SIH-210-10MG 10mg Cellular protectant Apoptosis $59.00 USD Add to Cart
Amifostine Small Molecules N/A SIH-210-50MG 50mg Cellular protectant Apoptosis $239.00 USD Add to Cart
Andrographolide Small Molecules N/A SIH-220-100MG 100mg Induces mitochondrial -mediated apoptosis in lymphoma cells Apoptosis $33.00 USD Add to Cart
Andrographolide Small Molecules N/A SIH-220-500MG 500mg Induces mitochondrial -mediated apoptosis in lymphoma cells Apoptosis $135.00 USD Add to Cart
Anisomycin Small Molecules N/A SIH-266-10MG 10mg anoikis sensitizer Apoptosis $36.00 USD Add to Cart
Anisomycin Small Molecules N/A SIH-266-50MG 50mg anoikis sensitizer Apoptosis $145.00 USD Add to Cart
Antibiotic A-23187 Small Molecules N/A SIH-227-10MG 10mg Ca2+ ionophore Apoptosis $89.00 USD Add to Cart
Antibiotic A-23187 Small Molecules N/A SIH-227-50MG 50mg Ca2+ ionophore Apoptosis $325.00 USD Add to Cart
Apigenin Small Molecules N/A SIH-249-10MG 10mg Protein kinase inhibitor Apoptosis $36.00 USD Add to Cart
Apigenin Small Molecules N/A SIH-249-50MG 50mg Protein kinase inhibitor Apoptosis $129.00 USD Add to Cart
Betulinic Acid Small Molecules N/A SIH-221-10MG 10mg Induces mitochondrial permeability pore opening Apoptosis $52.00 USD Add to Cart
Betulinic Acid Small Molecules N/A SIH-221-50MG 50mg Induces mitochondrial permeability pore opening Apoptosis $199.00 USD Add to Cart
BIM/BOD (IN) Antibodies N/A SPC-113C 25μg Polyclonal Apoptosis $110.00 USD Add to Cart
BIM/BOD (IN) Antibodies N/A SPC-113D 100μg Polyclonal Apoptosis $250.00 USD Add to Cart
BIM/BOD (IN2) Antibodies N/A SPC-164C 25ug Polyclonal Apoptosis $135.00 USD Add to Cart
BIM/BOD (IN2) Antibodies N/A SPC-164D 100ug Polyclonal Apoptosis $285.00 USD Add to Cart
Brefeldin A Small Molecules N/A SIH-225-10MG 10mg Inhibits intracellular transport Apoptosis $138.00 USD Add to Cart
Brefeldin A Small Molecules N/A SIH-225-50MG 50mg Inhibits intracellular transport Apoptosis $345.00 USD Add to Cart
C2 Ceramide Small Molecules N/A SIH-232-10MG 10mg Cell permeable ceramide analog Apoptosis $75.00 USD Add to Cart
C2 Ceramide Small Molecules N/A SIH-232-50MG 50mg Cell permeable ceramide analog Apoptosis $255.00 USD Add to Cart
Camptothecin Small Molecules N/A SIH-242-100MG 100mg Topoisomerase I inhibitor Apoptosis $62.00 USD Add to Cart
Camptothecin Small Molecules N/A SIH-242-1G 1g Topoisomerase I inhibitor Apoptosis $315.00 USD Add to Cart
CAPE Small Molecules N/A SIH-263-50MG 50mg Inhibits NFkB activation Apoptosis $56.00 USD Add to Cart
CAPE Small Molecules N/A SIH-263-250MG 250mg Inhibits NFkB activation Apoptosis $229.00 USD Add to Cart
Cycloheximide Small Molecules N/A SIH-247-1G 1g Translation inhibitor Apoptosis $53.00 USD Add to Cart
Cycloheximide Small Molecules N/A SIH-247-5G 5g Translation inhibitor Apoptosis $135.00 USD Add to Cart
Cyclopamine Small Molecules N/A SIH-226-1MG 1mg Inhibits hedgehog signaling Apoptosis $89.00 USD Add to Cart
Cyclopamine Small Molecules N/A SIH-226-5MG 5mg Inhibits hedgehog signaling Apoptosis $355.00 USD Add to Cart
Cyclosporine Small Molecules N/A SIH-201-10MG 10mg Inhibits mitochondrial permeability pore opening Apoptosis $187.00 USD Add to Cart
Cyclosporine Small Molecules N/A SIH-201-50MG 50mg Inhibits mitochondrial permeability pore opening Apoptosis $575.00 USD Add to Cart
Cytochalasin D Small Molecules N/A SIH-241-1MG 1mg Disrupts actin filaments Apoptosis $69.00 USD Add to Cart
Cytochalasin D Small Molecules N/A SIH-241-5MG 5mg Disrupts actin filaments Apoptosis $295.00 USD Add to Cart
Deguelin Small Molecules N/A SIH-251-10MG 10mg Akt inhibitor Apoptosis $155.00 USD Add to Cart
Deguelin Small Molecules N/A SIH-251-50MG 50mg Akt inhibitor Apoptosis $599.00 USD Add to Cart
Deprenyl Small Molecules N/A SIH-209-100MG 100mg glyceraldehyde-3-phosphate dehydrogenase inhibitor Apoptosis $49.00 USD Add to Cart
Deprenyl Small Molecules N/A SIH-209-1G 1g glyceraldehyde-3-phosphate dehydrogenase inhibitor Apoptosis $137.00 USD Add to Cart
Dexamethasone Small Molecules N/A SIH-259-1G 1g Apoptosis inducing glucocorticoid Apoptosis $53.00 USD Add to Cart
Dexamethasone Small Molecules N/A SIH-259-5G 5g Apoptosis inducing glucocorticoid Apoptosis $219.00 USD Add to Cart
Difluoromethylornithine Small Molecules N/A SIH-200-10MG 10mg Inhibits polyamine biosynthesis Apoptosis $25.00 USD Add to Cart
Difluoromethylornithine Small Molecules N/A SIH-200-50MG 50mg Inhibits polyamine biosynthesis Apoptosis $92.00 USD Add to Cart
Docetaxel Small Molecules N/A SIH-240-10MG 10mg Microtubule stabilizing agent Apoptosis $89.00 USD Add to Cart
Docetaxel Small Molecules N/A SIH-240-50MG 50mg Microtubule stabilizing agent Apoptosis $369.00 USD Add to Cart
Ebselen Small Molecules N/A SIH-204-10MG 10mg Glutathione peroxidase mimic Apoptosis $38.00 USD Add to Cart
Ebselen Small Molecules N/A SIH-204-50MG 50mg Glutathione peroxidase mimic Apoptosis $109.00 USD Add to Cart
Epothilone B Small Molecules N/A SIH-238-1MG 1mg Microtubule stabilizing agent Apoptosis $399.00 USD Add to Cart
Epothilone B Small Molecules N/A SIH-238-5MG 5mg Microtubule stabilizing agent Apoptosis $699.00 USD Add to Cart
Etoposide Small Molecules N/A SIH-244-100MG 100mg Topoisomerase II inhibitor Apoptosis $73.00 USD Add to Cart
Etoposide Small Molecules N/A SIH-244-500MG 500mg Topoisomerase II inhibitor Apoptosis $279.00 USD Add to Cart
FCCP Small Molecules N/A SIH-222-10MG 10mg Inhibits mitochondrial oxidative phosphorylation Apoptosis $69.00 USD Add to Cart
FCCP Small Molecules N/A SIH-222-50MG 50mg Inhibits mitochondrial oxidative phosphorylation Apoptosis $275.00 USD Add to Cart
FK506 Small Molecules N/A SIH-214-10MG 10mg FKBP inhibitor Apoptosis $100.00 USD Add to Cart
FK506 Small Molecules N/A SIH-214-50MG 50mg FKBP inhibitor Apoptosis $425.00 USD Add to Cart
Forskolin Small Molecules N/A SIH-208-10MG 10mg Adenylate cyclase activator Apoptosis $95.00 USD Add to Cart
Forskolin Small Molecules N/A SIH-208-50MG 50mg Adenylate cyclase activator Apoptosis $459.00 USD Add to Cart
Fumonisin B1 Small Molecules N/A SIH-234-1MG 1mg Blocks sphingolipid biosynthesis Apoptosis $65.00 USD Add to Cart
Fumonisin B1 Small Molecules N/A SIH-234-5MG 5mg Blocks sphingolipid biosynthesis Apoptosis $264.00 USD Add to Cart
Hypericin Small Molecules N/A SIH-250-1MG 1mg Protein kinase C inhibitor Apoptosis $58.00 USD Add to Cart
Hypericin Small Molecules N/A SIH-250-10MG 10mg Protein kinase C inhibitor Apoptosis $395.00 USD Add to Cart
Ionomycin Small Molecules N/A SIH-228-1MG 1mg Ca2+ ionophore Apoptosis $69.00 USD Add to Cart
Ionomycin Small Molecules N/A SIH-228-5MG 5mg Ca2+ ionophore Apoptosis $288.00 USD Add to Cart
Irinotecan HCl Small Molecules N/A SIH-243-50MG 50mg Topoisomerase I inhibitor Apoptosis $99.00 USD Add to Cart
Irinotecan HCl Small Molecules N/A SIH-243-250MG 250mg Topoisomerase I inhibitor Apoptosis $359.00 USD Add to Cart
Lovastatin Small Molecules N/A SIH-256-10MG 10mg HMG-CoA reductase inhibitor Apoptosis $42.00 USD Add to Cart
Lovastatin Small Molecules N/A SIH-256-50MG 50mg HMG-CoA reductase inhibitor Apoptosis $172.00 USD Add to Cart
LY 294002 HCl Small Molecules N/A SIH-252-5MG 5mg PI 3-Kinase inhibitor Apoptosis $82.00 USD Add to Cart
LY 294002 HCl Small Molecules N/A SIH-252-25MG 25mg PI 3-Kinase inhibitor Apoptosis $329.00 USD Add to Cart
Mifepristone (RU486) Small Molecules N/A SIH-211-100MG 100mg Glucocorticoid antagonist Apoptosis $59.00 USD Add to Cart
Mifepristone (RU486) Small Molecules N/A SIH-211-500MG 500mg Glucocorticoid antagonist Apoptosis $219.00 USD Add to Cart
Mitomycin C Small Molecules N/A SIH-246-10MG 10mg DNA crosslinking and damaging agent Apoptosis $99.00 USD Add to Cart
Mitomycin C Small Molecules N/A SIH-246-50MG 50mg DNA crosslinking and damaging agent Apoptosis $399.00 USD Add to Cart
Myriocin (ISP-1) Small Molecules N/A SIH-233-5MG 5mg Blocks sphingolipid biosynthesis Apoptosis $65.00 USD Add to Cart
Myriocin (ISP-1) Small Molecules N/A SIH-233-25MG 25mg Blocks sphingolipid biosynthesis Apoptosis $174.00 USD Add to Cart
N,N-Dimethylsphingosine Small Molecules N/A SIH-235-5MG 5mg Inhibits sphingosine kinase Apoptosis $59.00 USD Add to Cart
N,N-Dimethylsphingosine Small Molecules N/A SIH-235-25MG 25mg Inhibits sphingosine kinase Apoptosis $239.00 USD Add to Cart
Necrostatin Small Molecules N/A SIH-213-10MG 10mg Inhibits necroptosis Apoptosis $65.00 USD Add to Cart
Necrostatin Small Molecules N/A SIH-213-50MG 50mg Inhibits necroptosis Apoptosis $185.00 USD Add to Cart
Nigericin Small Molecules N/A SIH-229-10MG 10mg Induces rapid intracellular acidification Apoptosis $139.00 USD Add to Cart
Nigericin Small Molecules N/A SIH-229-50MG 50mg Induces rapid intracellular acidification Apoptosis $475.00 USD Add to Cart
Phenylbutyrate Na Small Molecules N/A SIH-255-100MG 100mg Histone deacetylase inhibitor Apoptosis $45.00 USD Add to Cart
Phenylbutyrate Na Small Molecules N/A SIH-255-500MG 500mg Histone deacetylase inhibitor Apoptosis $54.00 USD Add to Cart
PK-11195 Small Molecules N/A SIH-224-5MG 5mg Mitochondrial benzodiazepine receptor ligand Apoptosis $51.00 USD Add to Cart
PK-11195 Small Molecules N/A SIH-224-25MG 25mg Mitochondrial benzodiazepine receptor ligand Apoptosis $225.00 USD Add to Cart
PUMA (CT) Antibodies N/A SPC-166C 25ug Polyclonal Apoptosis $135.00 USD Add to Cart
PUMA (CT) Antibodies N/A SPC-166D 100ug Polyclonal Apoptosis $285.00 USD Add to Cart
PUMA (NT) Antibodies N/A SPC-165C 25ug Polyclonal Apoptosis $135.00 USD Add to Cart
PUMA (NT) Antibodies N/A SPC-165D 100ug Polyclonal Apoptosis $285.00 USD Add to Cart
Puromycin Small Molecules N/A SIH-248-50MG 50mg Translation inhibitor Apoptosis $43.00 USD Add to Cart
Puromycin Small Molecules N/A SIH-248-250MG 250mg Translation inhibitor Apoptosis $175.00 USD Add to Cart
R(-)-Gossypol Small Molecules N/A SIH-223-10MG 10mg Bcl-2 inhibitor Apoptosis $125.00 USD Add to Cart
R(-)-Gossypol Small Molecules N/A SIH-223-50MG 50mg Bcl-2 inhibitor Apoptosis $495.00 USD Add to Cart
Rapamycin Small Molecules N/A SIH-212-5MG 5mg mTOR inhibitor Apoptosis $119.00 USD Add to Cart
Rapamycin Small Molecules N/A SIH-212-25MG 25mg mTOR inhibitor Apoptosis $299.00 USD Add to Cart
Resveratrol Small Molecules N/A SIH-264-100MG 100mg Antioxidant Apoptosis $45.00 USD Add to Cart
Resveratrol Small Molecules N/A SIH-264-500MG 500mg Antioxidant Apoptosis $185.00 USD Add to Cart
Retinoic acid Small Molecules N/A SIH-258-50MG 50mg Retinoid RAR agonist Apoptosis $22.00 USD Add to Cart
Retinoic acid Small Molecules N/A SIH-258-250MG 250mg Retinoid RAR agonist Apoptosis $49.00 USD Add to Cart
Simvastatin Small Molecules N/A SIH-257-50MG 50mg HMG-CoA reductase inhibitor Apoptosis $99.00 USD Add to Cart
Simvastatin Small Molecules N/A SIH-257-250MG 250mg HMG-CoA reductase inhibitor Apoptosis $395.00 USD Add to Cart
Sphingosine Small Molecules N/A SIH-202-25MG 25mg Protein Kinase C inhibitor Apoptosis $89.00 USD Add to Cart
Sphingosine Small Molecules N/A SIH-202-100MG 100mg Protein Kinase C inhibitor Apoptosis $265.00 USD Add to Cart
Staurosporine Small Molecules N/A SIH-253-250UG 250ug Protein kinase inhibitor Apoptosis $105.00 USD Add to Cart
Staurosporine Small Molecules N/A SIH-253-1MG 1mg Protein kinase inhibitor Apoptosis $255.00 USD Add to Cart
Sulindac Sulfide Small Molecules N/A SIH-261-10MG 10mg NFkB inhibitor Apoptosis $89.00 USD Add to Cart
Sulindac Sulfide Small Molecules N/A SIH-261-50MG 50mg NFkB inhibitor Apoptosis $319.00 USD Add to Cart
Sulindac Sulfone Small Molecules N/A SIH-262-10MG 10mg Modulates beta-catenin-mediated effects Apoptosis $99.00 USD Add to Cart
Sulindac Sulfone Small Molecules N/A SIH-262-50MG 50mg Modulates beta-catenin-mediated effects Apoptosis $319.00 USD Add to Cart
Taxol Small Molecules N/A SIH-239-10MG 10mg Microtubule stabilizing agent Apoptosis $89.00 USD Add to Cart
Taxol Small Molecules N/A SIH-239-50MG 50mg Microtubule stabilizing agent Apoptosis $349.00 USD Add to Cart
TPCK Small Molecules N/A SIH-207-500MG 500mg Serine protease inhibitor Apoptosis $99.00 USD Add to Cart
TPEN Small Molecules N/A SIH-231-100MG 100mg Intracellular Zn2+ chelator Apoptosis $89.00 USD Add to Cart
TPEN Small Molecules N/A SIH-231-500MG 500mg Intracellular Zn2+ chelator Apoptosis $349.00 USD Add to Cart
Triacsin C Small Molecules N/A SIH-203-100UG 100ug Fatty acyl-CoA synthase inhibitor Apoptosis $89.00 USD Add to Cart
Triacsin C Small Molecules N/A SIH-203-1MG 1mg Fatty acyl-CoA synthase inhibitor Apoptosis $379.00 USD Add to Cart
Trichostatin A Small Molecules N/A SIH-254-1MG 1mg Histone deacetylase inhibitor Apoptosis $122.00 USD Add to Cart
Trichostatin A Small Molecules N/A SIH-254-5MG 5mg Histone deacetylase inhibitor Apoptosis $476.00 USD Add to Cart
Troglitazone Small Molecules N/A SIH-260-10MG 10mg PPARgamma agonist Apoptosis $89.00 USD Add to Cart
Troglitazone Small Molecules N/A SIH-260-50MG 50mg PPARgamma agonist Apoptosis $379.00 USD Add to Cart
TSP23 Antibodies Tsp232A SMC-194D 100ug Monoclonal Apoptosis, Chaperones, Heat Shock $265.00 USD Add to Cart
U-74389G Small Molecules N/A SIH-205-100MG 100mg Free radical scavenger Apoptosis $95.00 USD Add to Cart
U-74389G Small Molecules N/A SIH-205-500MG 500mg Free radical scavenger Apoptosis $449.00 USD Add to Cart
Ubiquitin Antibodies 5B9-B3 SMC-160A 50ug Monoclonal Apoptosis, Cell Signaling $143.00 USD Add to Cart
Ubiquitin Antibodies 6C11-B3 SMC-171A 50ug Monoclonal Apoptosis, Cell Signaling $143.00 USD Add to Cart
Ubiquitin Antibodies 6C11-B3 SMC-171B 200ug Monoclonal Apoptosis, Cell Signaling $291.00 USD Add to Cart
Ubiquitin Antibodies N/A SPC-119A 50ul Polyclonal Apoptosis, Cell Signaling $142.00 USD Add to Cart
Ubiquitin Antibodies N/A SPC-119B 200ul Polyclonal Apoptosis, Cell Signaling $291.00 USD Add to Cart
Valinomycin Small Molecules N/A SIH-230-10MG 10mg Induces loss of mitochondrial membrane potential Apoptosis $42.00 USD Add to Cart
Valinomycin Small Molecules N/A SIH-230-50MG 50mg Induces loss of mitochondrial membrane potential Apoptosis $139.00 USD Add to Cart
Z-Asp-CH2-DCB Small Molecules N/A SIH-206-10MG 10mg Caspase inhibitor Apoptosis $85.00 USD Add to Cart
Z-Asp-CH2-DCB Small Molecules N/A SIH-206-50MG 50mg Caspase inhibitor Apoptosis $349.00 USD Add to Cart
Zerumbone Small Molecules N/A SIH-265-10MG 10mg Enhances apoptotic effect of TRAIL Apoptosis $45.00 USD Add to Cart
Zerumbone Small Molecules N/A SIH-265-50MG 50mg Enhances apoptotic effect of TRAIL Apoptosis $185.00 USD Add to Cart
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