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Heat Shock Proteins

Heat shock proteins (HSPs) are a group of proteins that are present in all cells in all life forms. They have a variety of functions, but are mostly known as stress proteins because their expression is increased when the cells undergo various types of environmental stresses like heat, cold and oxygen deprivation.

Heat shock proteins also occur under non-stress conditions, essentially monitoring the cell’s proteins. They shuttle proteins from one compartment to another inside the cell (trafficking), and transport old proteins to removal areas inside the cell. Heat shock proteins are also believed to play a role in the presentation of specific proteins sites or peptides to the cell surface to help the immune system recognize diseased cells. HSPs also act as ‘chaperones,’ ensuring that the cell’s proteins are in the right conformations and in the right place at the right time. For example, HSPs help new or distorted proteins fold into their correct shape, which is essential for their function. Instrumental HSPs include but are not limited to Hsp90, Hsp70, Hsp60, Hsp40 and Hsp27.

For more detailed information on two of the main Heat Shock proteins - Hsp70 and Hsp90 - please see the following Focus Pages:

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Product Clone # Catalog # Size Description Price Place Order
17-AAG N/A SIH-100A 1mg Hsp90 inhibitor $180.00 USDBulk Quote
17-DMAG N/A SIH-114A 1mg Hsp90 inhibitor $180.00 USDBulk Quote
17-GMB-APA-GA N/A SIH-115A 1mg Hsp90 inhibitor $201.00 USDBulk Quote
Aha1 Antibody 4H9-D7 SMC-198D 100ug Anti-Aha1 $273.00 USDBulk Quote
Aha1 Antibody N/A SPC-183C 25ul Anti-Aha1 $149.00 USDBulk Quote
Aha1 Antibody N/A SPC-183D 100ul Anti-Aha1 $273.00 USDBulk Quote
Aha1 Antibody 25F2.D9 SMC-172C 25ug Anti-Aha1 $139.00 USDBulk Quote
Aha1 Antibody 25F2.D9 SMC-172D 100ug Anti-Aha1 $308.00 USDBulk Quote
Aha1 Antibody 25F2.D10 SMC-173C 25ug Anti-Aha1 $139.00 USDBulk Quote
Aha1 Antibody 25F2.D10 SMC-173D 100ug Anti-Aha1 $308.00 USDBulk Quote
Aha1 Protein (native, recombinant, human) N/A SPR-300A 50ug Native Aha1 Protein $201.00 USDBulk Quote
Aha1 Protein (native, recombinant, human) N/A SPR-300B 100ug Native Aha1 Protein $319.00 USDBulk Quote
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