Research Area

Oxidative Stress

Oxidative stress describes the steady state level of oxidative damage in a cell, tissue, or organ, caused by the reactive oxygen species. This damage can have a widespread effect on an entire organism, or on just a single molecule. It is caused by an imbalance between the production of reactive oxygen and a biological system's ability to readily detoxify the reactive intermediates or easily repair the resulting damage. All forms of life maintain a reducing environment within their cells through a constant input of metabolic energy which is preserved by enzymes. Disturbances in this normal redox state can cause toxic effects through the production of cell damaging peroxides and free radicals.

Research on human oxidative stress has led to links to many diseases such as atherosclerosis, Parkinson's disease and Alzheimer's disease and it may also be important in ageing. At the same time, reactive oxygen species can also be beneficial, as they are used by the immune system as a way to attack and kill pathogens

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Product	Category	Clone #	Catalog #	Size	Description	Research Area	Price	Place Order
Ambroxol HCl	Small Molecules	N/A	SIH-153-50MG	50mg	Free radical scavenger	Oxidative Stress	$62.00 USD	Add to Cart
Ambroxol HCl	Small Molecules	N/A	SIH-153-500MG	500mg	Free radical scavenger	Oxidative Stress	$99.00 USD	Add to Cart
Anti-HIF1 alpha, ESEE122	Antibodies	ESEE122	SMC-184C	25ug	Monoclonal	Cell Signaling, Oxidative Stress	$105.00 USD	Add to Cart
Anti-HIF1 alpha, ESEE122	Antibodies	ESEE122	SMC-184D	100ug	Monoclonal	Cell Signaling, Oxidative Stress	$255.00 USD	Add to Cart
Anti-HIF2 alpha, EP190b	Antibodies	EP190b	SMC-185C	25ug	Monoclonal	Cell Signaling, Oxidative Stress	$105.00 USD	Add to Cart
Anti-HIF2 alpha, EP190b	Antibodies	EP190B	SMC-185D	100ug	Monoclonal	Cell Signaling, Oxidative Stress	$255.00 USD	Add to Cart
bis-BHT	Small Molecules	N/A	SIH-154-100MG	100mg	Phenolic antioxidant	Oxidative Stress	$39.00 USD	Add to Cart
bis-BHT	Small Molecules	N/A	SIH-154-500MG	500mg	Phenolic antioxidant	Oxidative Stress	$79.00 USD	Add to Cart
Cu/Zn SOD, human	Antibodies	N/A	SPC-116C	25μg	Polyclonal	Oxidative Stress	$148.00 USD	Add to Cart
Cu/Zn SOD, human	Antibodies	N/A	SPC-116D	100μg	Polyclonal	Oxidative Stress	$299.00 USD	Add to Cart
Cu/Zn SOD, rat	Antibodies	N/A	SPC-115D	100μg	Polyclonal	Oxidative Stress	$299.00 USD	Add to Cart
Cu/Zn SOD, rat	Antibodies	N/A	SPC-115C	25μg	Polyclonal	Oxidative Stress	$148.00 USD	Add to Cart
DMPO	Small Molecules	N/A	SIH-324-125MG	125mg	Nitrone adduct formation	Oxidative Stress	$129.00 USD	Add to Cart
DMPO	Small Molecules	N/A	SIH-324-25MG	25mg	Nitrone adduct formation	Oxidative Stress	$29.00 USD	Add to Cart
DMPO, N1664A	Antibodies	N1664A	SMC-189D	100ug	Monoclonal	Oxidative Stress	$295.00 USD	Add to Cart
DMPO: Biotin	Antibodies	N1664A	SMC-191D	100ug	Monoclonal	Oxidative Stress	$315.00 USD	Add to Cart
DMPO: FITC	Antibodies	N1664A	SMC-190D	100ug	Monoclonal	Oxidative Stress	$315.00 USD	Add to Cart
DNA Damage, 8-OH-dG EIA kit	Kits	N/A	SKT-120-480	5x96 well	8-OHdG detection	Oxidative Stress	$1,399.00 USD	Add to Cart
DNA Damage, 8-OH-dG EIA kit	Kits	N/A	SKT-120-96	96-well	8-OHdG detection	Oxidative Stress	$380.00 USD	Add to Cart
DNA/RNA Damage	Antibodies	15A3	SMC-155C	25ug	Monoclonal	Oxidative Stress, Post-translational Modifications	$124.00 USD	Add to Cart
DNA/RNA Damage	Antibodies	15A3	SMC-155D	100ug	Monoclonal	Oxidative Stress, Post-translational Modifications	$265.00 USD	Add to Cart
EC SOD	Antibodies	4GG11G6	SMC-167C	25ug	Monoclonal	Oxidative Stress	$139.00 USD	Add to Cart
EC SOD	Antibodies	4GG11G6	SMC-167D	100ug	Monoclonal	Oxidative Stress	$280.00 USD	Add to Cart
FIH, FIH162C	Antibodies	FIH 162c	SMC-182D	100ug	Monoclonal	Cell Signaling, Oxidative Stress	$285.00 USD	Add to Cart
Hinokitiol	Small Molecules	N/A	SIH-151-50MG	50mg	Iron Chelator antioxidant	Oxidative Stress	$52.00 USD	Add to Cart
Hinokitiol	Small Molecules	N/A	SIH-151-250MG	250mg	Iron Chelator antioxidant	Oxidative Stress	$165.00 USD	Add to Cart
HO-1	Antibodies	1F12-A6	SMC-131C	25ug	Monoclonal	Chaperones, Heat Shock, Organelle Markers, Oxidative Stress	$141.00 USD	Add to Cart
HO-1	Antibodies	1F12-A6	SMC-131D	100ug	Monoclonal	Chaperones, Heat Shock, Organelle Markers, Oxidative Stress	$289.00 USD	Add to Cart
HO-1	Antibodies	N/A	SPC-112C	25ug	Polyclonal	Chaperones, Heat Shock, Oxidative Stress	$109.00 USD	Add to Cart
HO-1	Antibodies	N/A	SPC-112D	100ug	Polyclonal	Chaperones, Heat Shock, Oxidative Stress	$238.00 USD	Add to Cart
HO-1 ELISA Kit	Kits	N/A	SKT-111	96-well	ELISA kit used to quantitate teh HO-1 concentration in samples	Oxidative Stress	$499.00 USD	Add to Cart
Idebenone	Small Molecules	N/A	SIH-150-100MG	100mg	Quinone antioxidant and free radical scavenger	Oxidative Stress	$259.00 USD	Add to Cart
Idebenone	Small Molecules	N/A	SIH-150-20MG	20mg	Quinone antioxidant and free radical scavenger	Oxidative Stress	$65.00 USD	Add to Cart
MCI-186	Small Molecules	N/A	SIH-152-250MG	250mg	MCI-187	Oxidative Stress	$299.00 USD	Add to Cart
MCI-186	Small Molecules	N/A	SIH-152-50MG	50mg	MCI-186	Oxidative Stress	$79.00 USD	Add to Cart
MDC1	Antibodies	P2B11	SMC-197D	100ug	Mononclonal	Oxidative Stress	$265.00 USD	Add to Cart
Mn SOD (Human) (Recombinant, His-tag)	Proteins	N/A	SPR-131C	2x 100ug	his-tag	Oxidative Stress	$1,350.00 USD	Add to Cart
Mn SOD (Human) (Recombinant, His-tag)	Proteins	N/A	SPR-131B	100ug	his-tag	Oxidative Stress	$750.00 USD	Add to Cart
Mn SOD (Human) (Recombinant, His-tag)	Proteins	N/A	SPR-131A	50ug	His-tag	Oxidative Stress	$405.00 USD	Add to Cart
Mn SOD (Rat) (Recombinant, His-tag without the transit sequence)	Proteins	N/A	SPR-130C	2x 100ug	His-tagged without leader sequence	Oxidative Stress	$1,350.00 USD	Add to Cart
Mn SOD (Rat) (Recombinant, His-tag without the transit sequence)	Proteins	N/A	SPR-130A	50ug	His-tagged without leader sequence	Oxidative Stress	$405.00 USD	Add to Cart
Mn SOD (Rat) (Recombinant, His-tag without the transit sequence)	Proteins	N/A	SPR-130B	100ug	His-tagged without leader sequence	Oxidative Stress	$750.00 USD	Add to Cart
Mn SOD, human	Antibodies	N/A	SPC-118C	25μg	Polyclonal	Oxidative Stress	$148.00 USD	Add to Cart
Mn SOD, human	Antibodies	N/A	SPC-118D	100μg	Polyclonal	Oxidative Stress	$299.00 USD	Add to Cart
Mn SOD, rat	Antibodies	N/A	SPC-117D	100μg	Polyclonal	Oxidative Stress	$299.00 USD	Add to Cart
Mn SOD, rat	Antibodies	N/A	SPC-117C	25μg	Polyclonal	Oxidative Stress	$148.00 USD	Add to Cart
Nitrotyrosine	Antibodies	39B6	SMC-154D	100ug	Monoclonal	Cell Signaling, Oxidative Stress, Post-translational Modifications	$297.00 USD	Add to Cart
Nitrotyrosine	Antibodies	39B6	SMC-154C	25ug	Monoclonal	Cell Signaling, Oxidative Stress, Post-translational Modifications	$145.00 USD	Add to Cart
Piperlongumine	Small Molecules	N/A	SIH-156-20MG	20mg	Apoptosis inducer in oxidative stressed cells	Oxidative Stress	$88.00 USD	Add to Cart
Piperlongumine	Small Molecules	N/A	SIH-156-100MG	100mg	Apoptosis inducer in oxidative stressed cells	Oxidative Stress	$299.00 USD	Add to Cart
TEMPO	Small Molecules	N/A	SIH-155-500MG	500mg	Stabilized free radical	Oxidative Stress	$23.00 USD	Add to Cart