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Showing 111–120 of 120 results

  • Tau Protein

    Human Recombinant Tau (K18) P301L Mutant Protein Pre-formed Fibrils

    Catalog No. SPR-330

    5 out of 5 based on 2 customer ratings
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    Expression System E. coli
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    SPR-330_Tau-Preformed-Fibrils-Protein-IHC-1.png
    Comparison of AT8 (pSer202/pThr205) tau inclusions in P301L mice injected with K18 PFFs and negative control.TEM of recombinant Tau (K18), P301L mutant Pre-formed Fibrils (PFFs)TEM of recombinant Tau (K18), P301L mutant Pre-formed Fibrils (PFFs)Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in tau Pre-formed fibrils (SPR-330). Tau Pre-formed fibrils (SPR-330) seed the formation of new tau fibrils when combined with tau monomers (SPR-327)SDS-PAGE of ~15 kDa Human Tau Protein K18/P301L Pre-formed Fibrils (SPR-330)

  • Alpha Synuclein E114C Mutant Pre-formed Fibrils: ATTO 488

    Human Recombinant Alpha Synuclein E114C Mutant Pre-formed Fibrils: ATTO 488

    Catalog No. SPR-518-A488

    0 out of 5 based on 0 customer ratings
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    Expression System E. coli
    Tags ATTO 488
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    SPR-518-A488_Alpha-Synuclein-E114C-Mutant-Pre-formed-Fibrils-ATTO-488-Protein-ICC-IF-neuronal-uptake-1.png
    Representative TEM image of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)Representative TEM image of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)Fluorescent signal of alpha-synuclein E114C-ATTO-488 PFFs (SPR-518-A88)In vitro seeding activity of human Alpha Synuclein wildtype monomer in ThT assay. (SPR-518-A88)Sedimentation assay on ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils. (SPR-518-A88)SDS-PAGE analysis of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)

  • Tau-383 (0N4R) Wild-Type Pre-formed Fibrils

    Human Recombinant Tau-383 (0N4R) Wild-Type Pre-formed Fibrils

    Catalog No. SPR-510

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    Expression System E. coli
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    SPR-510_Tau-383-0N4R-Wild-Type-Pre-formed-Fibrils-Protein-TEM-1.png
    Thioflavin T assay of Tau-383 (0N4R) Wild-Type Pre-formed Fibrils Protein (SPR-510)Sedimentation assay of Tau-383 (0N4R) Wild-Type Pre-formed Fibrils Protein (SPR-510)AFM of Tau-383 (0N4R) Wild-Type Pre-formed Fibrils Protein (SPR-510)SDS-PAGE of Tau-383 (0N4R) Wild-Type Pre-formed Fibrils Protein (SPR-510)

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)

    Catalog No. SPR-322

    5 out of 5 based on 1 customer rating
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    Expression System E. coli
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    SPR-322_Alpha-Synuclein-Protein-Preformed-Fibrils-Protein-TEM-7.png
    Αlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.StressMarq’s Alpha Synuclein PFFs (red) cat#SPR-322, were shown to be taken up by SH-SY5Y cells and transmitted to neuronal iPSCs within 14 days.SDS-Page of Type 1 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-322)Type 1 alpha synuclein Pre-formed Fibrils (SPR-322) seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) as shown by increased fluorescence intensity by Thioflavin T over time.Immunocytochemistry/Immunofluorescence of Human Alpha Synuclein Protein Protein (SPR-322)Mouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFsMouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFs cause endogenous alpha synuclein phosphorylationTEM of Type 1 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-322)IHC of Sprague-Dawley rat brain injected with Type 1 human alpha synuclein Pre-formed Fibrils (SPR-322)Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).Toxicity results comparing Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2) and Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Protein Monomers (Type 1)

    Catalog No. SPR-321

    5 out of 5 based on 1 customer rating
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    Expression System E. coli
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    SPR-321_Alpha-Synuclein-Protein-Monomer-Thioflavin-T-assay-1.png
    SDS-Page of huma alpha synuclein monomer (SPR-321)

  • Alpha Synuclein A90C Mutant Monomers

    Human Recombinant Alpha Synuclein A90C Mutant Monomers

    Catalog No. SPR-478

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    Expression System E. coli
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    SPR-478_Alpha-Synuclein-A90C-Mutant-Monomers-Protein-FRET-1.png
    Coomassie stain of Alpha Synuclein A90C Monomers (SPR-478)Fibril formation of Alpha Synuclein A90C Monomers (SPR-478)AFM of Alpha Synuclein A90C Monomers (SPR-478)Seeding Activity of Alpha Synuclein A90C Monomers (SPR-478)

  • Alpha Synuclein Protein

    Human Recombinant N-Terminal Acetylated Alpha Synuclein Pre-formed Fibrils (Type 1)

    Catalog No. SPR-332

    5 out of 5 based on 1 customer rating
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    Expression System E. coli
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    SPR-332_N-Terminal-Acetylated-Alpha-Synuclein-Fibril-Protein-TEM-1.png
    TEM of N-acetylated alpha synuclein PFFsThioflavin T Seeding Assay of N-Terminal Acetylated Alpha Synuclein Pre-formed Fibrils (SPR-332)

  • Alpha Synuclein E114C Mutant Monomers: ATTO 488

    Human Recombinant Alpha Synuclein E114C Mutant Monomers: ATTO 488

    Catalog No. SPR-517-A488

    0 out of 5 based on 0 customer ratings
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    Expression System E. coli
    Tags ATTO 488
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    SPR-517-A488_Alpha-Synuclein-E114C-Mutant-Monomers-ATTO-488-Protein-SDS-Page-1.png
    Fibril formation of ATTO-488 conjugated alpha-synuclein E114C monomers. (SPR-517-A88)

  • Alpha Synuclein Pre-formed Fibrils: Biotinylated (C-terminus)

    Human Recombinant Alpha Synuclein Pre-formed Fibrils: Biotinylated (C-terminus)

    Catalog No. SPR-508

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    Expression System E. coli
    Tags C-terminal 15 amino acid tag: biotinylated
    SKU: SPR-508 Category:

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    SPR-508_Human-Recombinant-Alpha-Synuclein-Protein-Pre-formed-Fibrils-Biotinylated-C-Terminus-Protein-TEM-1.png
    Sedimentation assay on Alpha Synuclein Pre-formed Fibrils: Biotinylated (C-Terminus) (SPR-508).ThT assay of Human Recombinant Alpha Synuclein Protein Fibrils: Biotinylated (SPR-508).Biotinylation assay on purified Alpha Synuclein Monomers: Biotinylated (SPR-507).TEM of Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils: Biotinylated (C-Terminus) (SPR-508).AFM of Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils: Biotinylated (C-Terminus) (SPR-508).SDS-PAGE of Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils: Biotinylated (C-Terminus) (SPR-508).

  • Alpha Synuclein Monomers: Biotinylated (C-terminus)

    Human Recombinant Alpha Synuclein Monomers: Biotinylated (C-terminus)

    Catalog No. SPR-507

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    Expression System E. coli
    Tags C-terminal 15 amino acid tag: biotinylated
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    SPR-507_Human-Recombinant-Alpha-Synuclein-Protein-Monomers-Biotinylated-C-Terminus-Protein-SDS-Page-1.png
    Biotinylation assay on purified Alpha Synuclein Monomers: Biotinylated (SPR-507).ThT assay of Human Recombinant Alpha Synuclein Protein Monomers: Biotinylated (SPR-507).