Alzheimer's Disease

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  • Alpha Synuclein E114C Mutant Pre-formed Fibrils: ATTO 488

    Human Recombinant Alpha Synuclein E114C Mutant PFFs: ATTO 488

    Catalog No. SPR-518-A488

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    Expression System E. coli
    Tags ATTO 488
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    SPR-518-A488_Alpha-Synuclein-E114C-Mutant-Pre-formed-Fibrils-ATTO-488-Protein-ICC-IF-neuronal-uptake-1.png
    Representative TEM image of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)Representative TEM image of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)Fluorescent signal of alpha-synuclein E114C-ATTO-488 PFFs (SPR-518-A88)In vitro seeding activity of human Alpha Synuclein wildtype monomer in ThT assay. (SPR-518-A88)Sedimentation assay on ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils. (SPR-518-A88)SDS-PAGE analysis of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)

  • Alpha Synuclein Filaments

    Human Recombinant Alpha Synuclein Filaments

    Catalog No. SPR-450

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    Expression System E. coli
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    SKU: SPR-450 Category:

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    SPR-450_Alpha-Synuclein-Protein-Filaments-Protein-TEM-2.png
    TEM of Active Human Recombinant Alpha Synuclein Protein Filaments (SPR-450)

  • Alpha Synuclein Monomers

    Mouse Recombinant Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-323

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    Expression System E. coli
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    SPR-323_Alpha-Synuclein-Protein-IHC-1.png
    Mouse alpha Synuclein monomers (SPR-323) form new alpha synuclein fibrils through the seeding activity of Type 1 alpha synuclein pre-formed fibrils (SPR-324) as shown by increased fluorescence intensity by Thioflavin T over time.SDS-Page of Mouse Recombinant Alpha Synuclein Protein Monomer (SPR-323)

  • Alpha Synuclein Monomers

    Rat Recombinant Alpha Synuclein Monomers

    Catalog No. SPR-481

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    Expression System E. coli
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    SPR-481_Alpha-Synuclein-Monomer-Protein-SDS-PAGE-1.png
    Thioflavin T Fluorescence Activity for Rat Alpha Synuclein Protein (SPR-481)

  • Alpha Synuclein Monomers: Biotinylated

    Human Recombinant Alpha Synuclein Monomers: Biotinylated (C-terminus)

    Catalog No. SPR-507

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    Expression System E. coli
    Tags C-terminal 15 amino acid tag: biotinylated
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    SPR-507_Human-Recombinant-Alpha-Synuclein-Protein-Monomers-Biotinylated-C-Terminus-Protein-SDS-Page-1.png
    Biotinylation assay on purified Alpha Synuclein Monomers: Biotinylated (SPR-507).ThT assay of Human Recombinant Alpha Synuclein Protein Monomers: Biotinylated (SPR-507).

  • Alpha Synuclein N-Terminal Acetylated Monomers

    Human Recombinant N-Terminal Acetylated Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-331

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    Expression System E. coli
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    SPR-331_N-Terminal-Acetylated-Alpha-Synuclein-Monomer-Protein-Western-Blot-1.png
    Thioflavin T Seeding Assay of N-Terminal Acetylated Alpha Synuclein Monomers (SPR-331)

  • Alpha Synuclein N-Terminal Acetylated Pre-formed Fibrils

    Human Recombinant N-Terminal Acetylated Alpha Synuclein PFFs (Type 1)

    Catalog No. SPR-332

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    Expression System E. coli
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    SPR-332_N-Terminal-Acetylated-Alpha-Synuclein-Fibril-Protein-TEM-1.png
    TEM of N-acetylated alpha synuclein PFFsThioflavin T Seeding Assay of N-Terminal Acetylated Alpha Synuclein Pre-formed Fibrils (SPR-332)

  • Anti-Alpha Synuclein N-terminal Antibody [11D4]

    Mouse Anti-Human Alpha Synuclein N-terminal Monoclonal IgG1

    Catalog No. SMC-621

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    Species Reactivity Hu, Ms, Rt
    Applications WB IHC ICC/IF FCM IP
    SKU: SMC-621 Categories: ,

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    SMC-621_Alpha-Synuclein-N-terminal_Antibody_11D4_WB_Human_Recombinant-Protein_1.png
    Mouse Anti-Alpha Synuclein N-terminal Antibody [11D4] used in Immunohistochemistry (IHC) on HumanBrain (SMC-621)Mouse Anti-Alpha Synuclein N-terminal Antibody [11D4] used in Dot Blot (DB) on HumanRecombinant Protein (SMC-621)Mouse Anti-Alpha Synuclein N-terminal Antibody [11D4] used in Western Blot (WB) on Rat, Mousebrain lysate (SMC-621)

  • Alpha Synuclein Oligomers

    Human Recombinant Alpha Synuclein Oligomers (Dopamine HCL Stabilized)

    Catalog No. SPR-466

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    Expression System E. coli
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    SPR-466_Alpha-Synuclein-Oligomers-Protein-TEM-1.png
    TEM of Human Recombinant Alpha Synuclein Oligomers (Dopamine HCL Stabilized) (SPR-466)HPLC of Alpha Synuclein Oligomers (SPR-466)LDH assay shows effect of alpha synuclein oligomers on mouse primary neuronsMTT assay shows effect of alpha synuclein oligomers on mouse primary neuronsCoomassie gel stain of alpha synuclein oligomer (SPR-466)

  • Alpha Synuclein Oligomers

    Human Recombinant Alpha Synuclein Oligomers (Epigallocatechin gallate (EGCG) Stabilized)

    Catalog No. SPR-469

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    Expression System E. coli
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    SPR-469_Alpha-Synuclein-Oligomers-Protein-TEM-1.png
    Thioflavin T assay shows that EGCG-stabilzed alpha synuclein oligomers do not seed aggregation of alpha synuclein monomersSDS-PAGE of EGCG-stabilized alpha synuclein oligomers (SPR-469)Native SDS-PAGE of EGCG-stabilized alpha synuclein oligomers (SPR-469)

  • Alpha Synuclein Oligomers

    Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable)

    Catalog No. SPR-484

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    Expression System E. coli
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    SPR-484_Alpha-Synuclein-Oligomers-Kinetcially-Stable-Protein-TEM-1.png
    Native PAGE of Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable) (SPR-484).Αlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Toxicity of Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable) (SPR-484).IHC of Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable) (SPR-484).

  • Alpha Synuclein Pre-formed Fibrils

    Mouse Recombinant Alpha Synuclein PFFs (Type 1)

    Catalog No. SPR-324

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    Expression System E. coli
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    SPR-324_Alpha-Synuclein-Protein-Preformed-Fibrils-ICC-IF-1.png
    IHC of mouse brain injected with alpha synuclein monomers and fibrilsIHC of mouse brain injected with alpha synuclein monomers and fibrilsIHC of Sprague-Dawley rat brain injected with Type 1 mouse alpha synuclein Pre-formed Fibrils (SPR-324)Mouse hippocampal neurons treated with mouse alpha synuclein PFFs show phosphorylationTEM of Type 1 mouse alpha synuclein Pre-formed Fibrils (SPR-324).Mouse Type 1 alpha synuclein Pre-formed Fibrils (SPR-324) seed the formation of new alpha Synuclein fibrils from the pool of alpha synuclein monomers (SPR-323) as shown by increased fluorescence intensity by Thioflavin T over time.TEM of Type 1 mouse alpha synuclein Pre-formed Fibrils (SPR-324).SDS-Page of Type 1 Mouse Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-324)

  • Alpha Synuclein Pre-formed Fibrils

    Rat Recombinant Alpha Synuclein PFFs

    Catalog No. SPR-482

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    Expression System E. coli
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    SPR-482_Alpha-Synuclein-Fibrils-Protein-TEM-1.png
    TEM of Rat Alpha Synuclein Pre-formed Fibrils (PFFS) (SPR-482).Thioflavin T Fluorescence Activity for Rat Alpha Synuclein Protein (SPR-482)

  • Alpha Synuclein Pre-formed Fibrils: ATTO 594

    Human Recombinant Alpha Synuclein PFFs: ATTO 594 (Type 1)

    Catalog No. SPR-322-A594

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    Expression System E. coli
    Tags ATTO 594
    SKU: SPR-322-A594 Category:

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    SPR-322-A594_Alpha-Synuclein-Protein-Protein-TEM-1.png
    Thioflavin T Assay for SPR-322-A594Human iPSC-derived neurons seeded with ATTO594 labelled alpha synuclein PFFs (SPR-322-A594)TEM of ATTO conjugated alpha syuclein pre-formed fibrils

  • Alpha Synuclein Pre-formed Fibrils: Biotinylated

    Human Recombinant Alpha Synuclein PFFs: Biotinylated (C-terminus)

    Catalog No. SPR-508

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    Expression System E. coli
    Tags C-terminal 15 amino acid tag: biotinylated
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    SPR-508_Human-Recombinant-Alpha-Synuclein-Protein-Pre-formed-Fibrils-Biotinylated-C-Terminus-Protein-TEM-1.png
    Sedimentation assay on Alpha Synuclein Pre-formed Fibrils: Biotinylated (C-Terminus) (SPR-508).ThT assay of Human Recombinant Alpha Synuclein Protein Fibrils: Biotinylated (SPR-508).Biotinylation assay on purified Alpha Synuclein Monomers: Biotinylated (SPR-507).TEM of Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils: Biotinylated (C-Terminus) (SPR-508).AFM of Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils: Biotinylated (C-Terminus) (SPR-508).SDS-PAGE of Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils: Biotinylated (C-Terminus) (SPR-508).

  • Alpha Synuclein pSer129 Monomers

    Human Recombinant Alpha Synuclein pSer129 Monomers (phosphorylated at position 129)

    Catalog No. SPR-520

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    Expression System E. coli
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    SPR-520_Alpha-Synuclein-pSer129-Monomers-Protein-SDS-Page-1.png
    Dot Blot of Alpha Synuclein pSer129 Monomers (SPR-520)Mass Spec Bar Graph of Alpha Synuclein pSer129 Monomers (SPR-520)Thioflavin T assay of Alpha Synuclein pSer129 Monomers (SPR-520)